Researchers at the University of Rochester are working on a method for rapid cancer diagnosis using SiMPore’s ultrathin nanomembranes. This technique, known as catch and display for liquid biopsies (CAD-LB), captures extracellular vesicles (EVs)—nano-sized carriers of cellular information—from minimally processed blood samples. By fluorescently labeling EVs caught in the membranes’ nanopores, CAD-LB enables quick detection […]
Application Notes
See how SiMPore’s nanomembrane-enabled products provide solutions for your research work.
Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using “Catch and Display” on Ultrathin Nanoporous Silicon Nitride Membranes
Extracellular vesicles (EVs) are lipid-bound particles shed by all cells. They are involved in cell-cell communication, but have recently gained significant interest for their potential use as diagnostics and as therapeutics. Researchers from multiple Universities recently published work demonstrating the capability of SiMPore’s Silicon Nanomembranes for catch-and-display of single EVs, enabling novel analyses of these nano-sized bio particles […]
University of Rochester Researchers Develop Lung-to-Brain Tissue Chips to Study Respiratory Disease Impact on the Brain
The University of Rochester has received a $7.1 million contract from the Biomedical Advanced Research and Development Authority (BARDA) to develop innovative tissue-on-chip technology. This groundbreaking research aims to explore the link between respiratory diseases, such as influenza, and neurological symptoms like brain fog. The three-year project uses microphysiological systems (MPS)—tiny chips that simulate human […]
Evaluating Time to Results for Particle Capture and Analysis on SiMPore Filters
Application Note: Impact of analytical filter surface on total analysis time – Bigger isn’t always better! Read the study
Consumer Water Pitcher – Microplastics Removal Challenge Study
Application Note: Microplastics in Drinking Water – Do Household Pitcher Filters Really Work?
Extracellular Vesicle Detection & Analysis by Silicon Nanomembrane-enabled Microfluidics
Application Note: A step-by-step introductory guide on the analysis of single extracellular vesicles enabled by µSiM-EV products
Spheroid Culture of HEK-293T using MicroBubble Array™ Products
Application Note: Single cell-derived spheroid cultures enabled by MicroBubble Array™ Products
How to Choose a TEM Window Grid
Application Note: Guidelines for selecting a TEM Window Grid