UR researchers develop new method for liquid biopsies

photo of doctor holding patients hand, University of Rochester and SiMPore logo shown on photo

UR researchers develop new method for liquid biopsies

December 10, 2024

Researchers at the University of Rochester are working on a method for rapid cancer diagnosis using SiMPore’s ultrathin nanomembranes. This technique, known as catch and display for liquid biopsies (CAD-LB), captures extracellular vesicles (EVs)—nano-sized carriers of cellular information—from minimally processed blood samples.

By fluorescently labeling EVs caught in the membranes’ nanopores, CAD-LB enables quick detection of cancer biomarkers and immune-modulatory proteins, supporting early diagnosis and tailored immunotherapies.

“CAD-LB is faster and simpler, making it ideal for clinical use,” says James McGrath, lead researcher and SiMPore co-founder.

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