SiMPore at Work

Authored by: Teagan Horan, Applications Scientist, SiMPore and Peng Miao, Applications Scientist, HORIBA Instruments Inc. Introduction USP788 is an accepted method by which to test parenteral drug products for the presence of subvisible particles 10 µm and larger. Method I utilizes light obscuration to detect and measure levels of these particles. When samples exceed the […]

At SiMPore, we provide the analytical tools for the consumer beverage industry to uncover answers and validate solutions when tackling the microplastics challenge in beverage products. SiMPore Filter Disks, comprising silicon nanomembrane technology feature precision-patterned, consistent pore geometry, enabling improved particle capture and analysis methodologies over other available filter options on the market. For this […]

As consumers become increasingly aware of the microplastic pollution problem, many are asking a critical question: does the pitcher filter on their kitchen counter actually protect them? Microplastic filtration — the process of physically removing microscopic plastic particles from water — has become a key consideration for health-conscious households. Yet until now, there has been […]

The biological impact of microplastics in human food and water sources is largely unknown, and drinking water sources are not exempt from microplastic contamination. Here, we demonstrate a streamlined approach for capturing, quantifying, and identifying microplastics in drinking water. We present an analytical workflow termed Silicon Nanomembrane Analysis Pipeline (SNAP) that takes advantage of novel silicon nitride nanomembranes […]

Researchers at the University of Rochester are working on a method for rapid cancer diagnosis using SiMPore’s ultrathin nanomembranes. This technique, known as catch and display for liquid biopsies (CAD-LB), captures extracellular vesicles (EVs)—nano-sized carriers of cellular information—from minimally processed blood samples. By fluorescently labeling EVs caught in the membranes’ nanopores, CAD-LB enables quick detection […]

Extracellular vesicles (EVs) are lipid-bound particles shed by all cells. They are involved in cell-cell communication, but have recently gained significant interest for their potential use as diagnostics and as therapeutics. Researchers from multiple Universities recently published work demonstrating the capability of SiMPore’s Silicon Nanomembranes for catch-and-display of single EVs, enabling novel analyses of these nano-sized bio particles […]

Check out what other researchers have done with SiMPore filters for microplastics capture and analysis.

Recent publications highlight the unique utility of SiMPore’s filters, which enable direct capture and analysis of microplastic particulates on the same filter without any burdensome transfers.

Two recent publications in the journal Advance Healthcare Materials feature SiMPore’s silicon nanomembranes in support of a modular and flexible tissue chip platform.

A poster created by SiMPore and Parverio related to joint work performed evaluating the filtration and imaging properties of filter membranes.